Survival in unresectable sinonasal undifferentiated carcinoma treated with concurrent intra-arterial cisplatin and radiation

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Survival in unresectable sinonasal undifferentiated carcinoma treated with concurrent intra-arterial cisplatin and radiation.

We report the successful use of RADPLAT to treat a patient with an unresectable T4N0 sinonasal undifferentiated carcinoma. This patient received 4 cycles of weekly intra-arterial cisplatin together with thiosulfate infusion with concurrent radiation therapy. Radiation therapy was given in 28 daily fractions to 54 Gy using intensity-modulated radiation therapy followed by a hypofractionated ster...

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Sinonasal undifferentiated carcinoma.

PURPOSE The purpose of this paper is to discuss the treatment and outcomes for patients with sinonasal undifferentiated carcinoma. METHODS Review of the pertinent literature. RESULTS Most series contain a limited number of patients treated with various combinations of surgery, radiotherapy (RT), and chemotherapy. Follow-up periods for disease-free patients are sometimes relatively short. Th...

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Survival Outcomes for Combined Modality Therapy for Sinonasal Undifferentiated Carcinoma.

Objective Sinonasal undifferentiated carcinoma is a rare and aggressive malignancy of the nasal cavity and paranasal sinuses. Multi-institutional studies examining outcomes of combined modality treatment versus other treatment modalities have not been performed. The objective of our study was to present outcomes for multimodality therapy through use of the National Cancer Database. Study Design...

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Sinonasal undifferentiated carcinoma: an update.

PURPOSE OF REVIEW Sinonasal undifferentiated carcinoma is a rare and extremely malignant tumor of the paranasal sinuses. Historically, treatment outcomes have been poor. This review presents recent data on the management of sinonasal undifferentiated carcinoma and examines treatment trends that may result in improved locoregional control and survival. RECENT FINDINGS Patients who receive aggr...

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Intra-arterial cisplatin with concomitant radiation for advanced hypopharyngeal cancer.

OBJECTIVES/HYPOTHESIS The current study evaluated the efficacy of radiation and concomitant high-dose superselective intra-arterial cisplatin infusion (RADPLAT) for patients with advanced hypopharyngeal cancer. STUDY DESIGN Retrospective, single-institutional study. METHODS Between February 2004 and October 2010, 43 patients with T2N0 or worse cancer were given superselective intra-arterial...

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ژورنال

عنوان ژورنال: World Journal of Clinical Cases

سال: 2015

ISSN: 2307-8960

DOI: 10.12998/wjcc.v3.i2.191